Date of Tips: 01/12/2025
Disclaimer The odds for these selections were correct at the time of publishing (14:22 01/12/2025) but may have changed since. Please check the latest price before placing your bet.
Arsenal FC
v Brentford FC 
Emirates Stadium
Premier League Matchday 14
03-12-2025 19:30
Arsenal Form
Brentford Form
Arsenal welcome Brentford to the Emirates Stadium on Wednesday evening in another all-London showdown, and this one arrives with plenty riding on it. The Premier League leaders are aiming to steady the ship after a draining run of big games, while the visitors are pushing to stay in the European conversation. So, the Arsenal vs Brentford prediction naturally becomes one of the key talking points heading into this midweek clash.
Kick-off comes at a moment when Arsenal’s long unbeaten spell is being tested by fatigue, and Brentford’s away form continues to hold them back. With both sides bringing clear strengths—and clear flaws—this derby feels like it could get lively fast.
Arsenal still have injury headaches at the back. William Saliba missed the Chelsea game after picking up a training knock, and even though further tests are planned, it would be a surprise to see him risked. His usual partner Gabriel Magalhaes is also out with a hamstring issue, leaving the league leaders without their first-choice pairing.
In attack, Leandro Trossard (muscle) and Kai Havertz (knee) remain unavailable. The good news for Mikel Arteta is that Noni Madueke, Martin Odegaard, and Viktor Gyokeres are all fit and pushing hard for starts. Gabriel Jesus, fresh from an ACL recovery, even made the bench on Sunday and could feature again. There’s also a chance Arteta rotates, with Myles Lewis-Skelly a potential starter as Riccardo Calafiori risks suspension with one more booking.
Brentford also arrive with a thin squad. On-loan Arsenal man Reiss Nelson cannot face his parent club. Beyond that, the Bees are missing Fabio Carvalho, Antoni Milambo, and Josh Dasilva, with all three sidelined until 2026 due to knee injuries. Keith Andrews has often used a five-man defence against Big Six opponents, so another tactical switch is very possible.
Raya; White, Mosquera, Hincapie, Lewis-Skelly; Odegaard, Zubimendi, Rice; Madueke, Gyokeres, Eze
Kelleher; Kayode, Collins, Van den Berg, Ajer, Henry; Yarmoliuk, Henderson; Damsgaard; Ouattara, Thiago
Arsenal’s home record this season has been outstanding. They’ve won nine of their 10 home games in all competitions and are on a run of seven straight home victories. They’ve also conceded only two Premier League home goals in the entire campaign. That defensive record—even without Saliba and Gabriel—sets a strong base.
Brentford, meanwhile, have lost five of their six league away matches, including their last two. They’ve kept just one away clean sheet this season. That alone points toward goals for Arsenal.
Even so, Brentford do carry real threat. Igor Thiago has been electric, hitting 10 Premier League goals in 13 games, the fastest any Brentford player has reached double digits in a season. He’ll fancy his chances against an improvised Arsenal back line.
Recommended angles:
Arsenal’s draw at Chelsea extended their unbeaten run to 17 games, but you could see the fatigue. Even so, their depth is superior, and players like Madueke, Odegaard, and Gyokeres should give them enough creativity and power.
Brentford’s biggest challenge will be surviving long spells without the ball. Their away form suggests they struggle with that, but Thiago’s sharpness means they should still carve out chances.
Match Prediction: Arsenal to win. Bet with bet365.
A tight Arsenal win feels the most realistic outcome.
Correct score lean:
Arsenal 2–1 Brentford
The Gunners’ attacking depth should get them over the line, but Thiago’s form suggests Brentford won’t leave empty-handed.
Correct Score Prediction: Arsenal 2–1 Brentford. Bet with bet365.
Over/Under Prediction: Over 2.5 Goals. Bet with bet365.
A simple, sensible combination:
This mirrors the patterns both clubs have shown throughout the season.
Bet Builder Tip: Arsenal to win, over 2.5 goals, and both teams to score – Yes. Bet with bet365.
Key Stats
18+. New customers only. Min deposit £20. Max One £10 Free Bet & two £5 Bet Builder Free Bets.. Qualifying Bets must be placed at odds of 1/1 (2.00) or greater. Paid as bonus tokens with Min 4/5 (1.80) odds req. Token 2& 3 are valid for Bet Builder only and are subject to min odds of 2/1 (3.00) T&Cs apply. GambleAware.org #ad
Visit our football previews & predictions page for more betting tips on upcoming matches.
Arsenal are favourites thanks to their dominant home form and deeper squad, but Brentford should still test them.
Yes, they have the firepower—especially with Thiago—to trouble Arsenal’s weakened centre-back pairing.
Madueke, Odegaard, and Gyokeres for Arsenal; Thiago for Brentford.
A moderate-to-high scoring game looks likely, with both teams capable of creating chances.