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Liverpool vs Atlético Madrid Odds Selection Odds Liverpool Win 4/6 Draw 3/1 Atlético Madrid Win 15/4 Date: 18/09/25Kick-off time:…
Liverpool FC
v Club Atlético de Madrid 
Anfield
UEFA Champions League LEAGUE_STAGE 
17-09-2025 19:00
Liverpool Form
Atleti Form
Date: 17/09/25
Kick-off time: 20:00
Venue: Anfield
The Champions League is back, and Anfield gets the spotlight straight away. Liverpool welcome Atlético Madrid in a matchup that always carries drama. These two have history, no shortage of fiery moments, and plenty of big names on show.
Liverpool are flying in the league and look sharp early in the season, while Atlético’s domestic form has been more of a stutter. Add in the Anfield atmosphere, and you can see why the Reds start as favourites. But we’ve seen Diego Simeone’s side spoil parties before… so could they spring another surprise?
Liverpool:
Jeremie Frimpong is touch-and-go with a knock, while new signing Alexander Isak could make his Champions League debut for the club. Imagine him scoring under the lights — the place would erupt. Everyone else looks fit, which means Klopp has a stacked bench to call on. Expect Salah, Wirtz, and Gakpo buzzing around up front, with Mac Allister pulling the strings in midfield.
Atlético Madrid:
Alex Baena misses out, and Jose Gimenez is still a fitness doubt, which is a worry given the firepower he’s up against. The good news? Julian Alvarez leads the line. He knows what it’s like to play in England, and Atlético will be banking on him to nick a goal. Still, without their defensive leader Gimenez, keeping Liverpool quiet feels like a tall order.
Likely Lineups
Liverpool (4-2-3-1): Alisson; Frimpong, Konate, Van Dijk, Robertson; Mac Allister, Szoboszlai; Salah, Wirtz, Gakpo; Isak.
Atlético Madrid (4-4-2): Oblak; Molina, Savic, Hermoso, Lino; De Paul, Koke, Saul, Carrasco; Morata, Alvarez.
I think it’s safe to say goals are coming in this one. Liverpool have scored in every home game so far this season, and their Champions League record at Anfield is ridiculous — seven wins from their last eight. Atlético? They’ve only managed four wins from their last fourteen away European trips. That’s not the best stat if you’re heading into a cauldron like this.
Betting angles worth considering:
So, how’s it going to play out? Liverpool will dominate possession, press high, and look to overwhelm Atlético early. Klopp’s men are ruthless at home, and if Isak starts, that front four is scary.
Atleti will sit deep, frustrate, and hope Alvarez or Morata can cause problems on the break. They’ll probably get a chance or two, but over ninety minutes, Liverpool’s quality should shine through.
Match Prediction: Liverpool to win. Bet with bet365.
I’m leaning towards 3-1 Liverpool. They’ve got the attacking firepower to score multiple goals, and Atlético’s defence doesn’t look watertight right now. Atleti might sneak one, but that’s about it.
Correct Score Prediction: Liverpool 3-1 Atlético Madrid. Bet with bet365.
The numbers point towards a lively one. Atlético have scored in nine of their last eleven away Champions League games. Liverpool rarely fail to score at Anfield. Put those together, and goals look guaranteed.
Over 3.5 goals is tempting if you want bigger value.
Over 2.5 goals feels safe.
Over/Under Prediction: Over 3.5 Goals. Bet with bet365.
Here’s a combo I like for this one:
That’s your Anfield special — attacking football, goals at both ends, and Salah doing Salah things.
Bet Builder Tip: Liverpool to Win, BTTS Yes, Salah Anytime Scorer & Over 2.5 Goals. Bet with bet365.
Key Stats
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Visit our football previews & predictions page for more betting tips on upcoming matches.
The match takes place on September 17, 2025, at Anfield, 20:00 kick-off.
Liverpool are favourites. Their home form and current momentum give them the edge.
A 3-1 Liverpool win looks the most realistic outcome.
Fans in England can watch live on TNT Sports. In Spain, the game will be shown on Movistar+.
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